Using data from real-world conditions in the Naoussa Valley, Greece, the model simulates how medflies and released sterile males behave and disperse in complex local terrain, to assess how variables like fruit type, landscape structure, release frequency, and male quality affect SIT success. Furthermore the article provides insight into when and where to release sterile males for maximum impact: a particularly important information for emergency responses, isolated outbreak management, and preventive actions near high-risk areas such as ports or fruit markets.

The adapted PESTonFARM model bridges a crucial gap in applying SIT on a local scale. It empowers pest managers and researchers with the ability to design data-informed, site-specific strategies—an essential advancement for integrated pest management (IPM) in diverse European landscapes.